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Oxymorphone is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. Oxymorphone belongs to the group of medicines called narcotic analgesics (pain medicines). It acts in the central nervous system (CNS) to relieve pain. Many of its side effects are also caused by its actions in the CNS.
Oxymorphone extended-release tablets are used to relieve moderate to severe pain in patients requiring continuous, around-the-clock treatment for a long period of time, and should not be used if you need pain medicine for just a short time, such as when recovering from surgery. Do not use this medicine to relieve mild pain, or in situations where a non-narcotic medication is effective. This medicine should not be used to treat pain that you only have once in a while or “as needed”.
When oxymorphone is used for a long time, it may become habit-forming (causing mental or physical dependence). However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by reducing the dose gradually over a period of time before treatment is stopped completely.
This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.
This product is available in the following dosage forms:
Tablet, Extended Release
Opana ER FAQs
Can you break Opana in half?
OPANA ER TABLETS are to be swallowed whole, and are not to be broken, chewed, crushed or dissolved. Taking broken, chewed, crushed or dissolved OPANA ER TABLETS could lead to the rapid release and absorption of a potentially fatal dose of oxymorphone.
Why do you take oxymorphone on an empty stomach?
It’s best to take oxymorphone on an empty stomach at least 1 hour before or 2 hours after eating. Food can cause more oxymorphone to accumulate in your body which can put you at higher risk for side effects. Avoid driving or other tasks that require you to be alert until you know how this medication affects you.
How many oxymorphone can you take in a day?
Adults—At first, 10 to 20 milligrams (mg) every 4 to 6 hours per day. Your doctor may adjust your dose as needed. Children—Use is not recommended.
What is similar to Opana?
Opana and Roxicodone are both in a class of drugs called opiate analgesics or narcotics. They’re used to treat moderate to severe pain after other drugs haven’t worked to ease the pain. Both medications work on the opioid receptors in your brain.
What is the difference between morphine and oxymorphone?
The oral oxymorphone formulations are roughly three times more potent than oral morphine. It is more lipophilic than morphine and, thus, may more easily cross the blood-brain barrier because it differs from morphine having a ketone-group substituent at the C-6 position.
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